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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-01007
- 製品名称
- VEGFC Protein, Human, Recombinant (His)
- タンパク質名
- VEGFC
- Species
- Human
- HOST
- HEK293 Cells
- 5μg: -
- お問い合わせ
Overview
| Synonyms | LMPH1D, VEGF-C, Flt4-L, vascular endothelial growth factor C, VRP |
|---|---|
| Characteristics | 1. Measured by its binding ability in a functional ELISA. Immobilized VEGF C-his at 2 μg/mL (100 μL/well) can bind VEGFR3 hFc, the EC50 of VEGFR3 hFc is 2-15 ng/mL. 2. Scatchard analysis showed the affinity constant (Kd) of recombinant human VEGF-C bound to recombinant human VEGFR3 was 1.4 nM. 3. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 0.1-0.5 μg/mL. 4. Captured VEGFR3/FLT4 Protein, Human on anti-Human IgG Fc via CM5 Chip?can?bind VEGF-C with an affinity constant of 31.82 pM as determined?in a SPR assay (Routinely tested). |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 99.40% |
| Description | VEGFC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P49767. |
| Reference | Joukov V, et al. (1997) Vascular endothelial growth factors VEGF-B and VEGF-C. J Cell Physiol. 173(2): 211-5.,Anisimov A, et al. (2009) Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle. Circ Res. 104(11): 1302-12.,Su JL, et al. (2007) The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer. 96(4): 541-5. |
| URL | https://www.targetmol.com/recombinant-protein/vegf_c_protein_human_recombinant_his_tag_ |
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