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【TargetMol】新しい化合物ライブラリのご紹介

  • 2025/06/27
  • サプライヤニュース

新着情報一覧へ

 
 
 

A New Compound Library Is Now Available:

L5310——Mitochondrial Membrane Protein-Targeted Compound Library

 

Mitochondria are known as the "powerhouses" of the cell, responsible for producing ATP to meet cellular energy demands. They are composed of a double-membrane structure, with both the outer and inner membranes containing a variety of functional membrane proteins. These mitochondrial membrane proteins play essential roles in maintaining normal cellular physiology, including energy metabolism, fatty acid oxidation, and oxidative phosphorylation.

Studies have shown that dysfunction of mitochondrial membrane proteins is closely associated with the onset and progression of various diseases. In neurodegenerative disorders (such as Alzheimer’s disease and Parkinson’s disease), metabolic diseases (such as diabetes and obesity), cardiovascular conditions, and hereditary mitochondrial disorders, the dysregulation of key membrane proteins—including components of the electron transport chain, ATP synthase, voltage-dependent anion channels (VDAC), and Bcl-2 family proteins—plays a central role. These findings offer new therapeutic targets; modulating the function of these proteins with small molecules can effectively influence mitochondrial-related physiological and pathological processes, providing new strategies for disease treatment.

 

How can we precisely target these "elusive" mitochondrial membrane proteins? This has become the key to breakthrough therapies!

TargetMol is offering the brand-new Mitochondrial Membrane Protein-Targeted Compound Library, specially designed to accelerate your target validation and lead compound screening.

 
Advantages of L5310
1. TargetMol offers 215 compounds targeting mitochondrial membrane proteins, suitable for high-throughput screening (HTS) and high-content screening (HCS);

2. The targets include electron transport chain complexes, ATP synthase, VDAC, Bcl-2, MAO, and others;

3. Structurally diverse, medicinally active, and cell permeable;

4. Rich documentation with structure, target, IC50 value and biological activity description;

5. NMR and HPLC/LCMS validated to ensure high purity.

Related Compound Libraries 

Catalog No.
Product Name
TargetMol Link
 
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TargetMol(ターゲットモル)社について

本社所在地
アメリカ マサチューセッツ州
URL
https://www.targetmol.com/

TargetMolは、ボストンに本社を置く低分子およびスクリーニングライブラリのサプライヤです。ライフサイエンス試薬、阻害剤、活性剤、実験用および科学用の天然化合物を提供しています。ポートフォリオには、6,000を超える化合物/阻害剤(カタログ)と80種類を超える化合物ライブラリがあります。

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