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【TargetMol】新製品(3月版)のご紹介
- 2025/04/30
- サプライヤニュース
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| New Compound | March |
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KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.
Research Areas: Cardiovascular Disease Targets: Others |
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QPX7728 disodium (Xeruborbactam disodium) is a cyclic boronate inhibitor of many serine and metal-β-lactamases with antibacterial activity, used in research on bacterial infections.
Research Areas: Bacterial Infections Targets: Others |
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BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.
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APJ receptor agonist 8 is a small molecule agonist of the APJ receptor, enhancing load-independent cardiac contractility in isolated perfused rat hearts. It mimics the action of the endogenous ligand Apelin and has an EC50 of 21.5 µM.
Research Areas: Cardiovascular Disease Targets: Apelin Receptor (APJ) |
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iHCK-37 (ASN05260065) is a selective Hck inhibitor with antitumor activity, blocking HIV-1 viral replication. iHCK-37 reduces PI3K/AKT and MAPK/ERK pathway activation after erythropoietin induction in high Hck-expressing cells, useful in chronic myelogenous leukemia (CML) research.
Research Areas: Infection; Cancer Targets: Src |
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Lodelaben (Declaben, SC-39026) is a reversible, non-competitive inhibitor of human neutrophil elastase (HNE), characterized by specificity and potency (IC50=0.5 μM, Ki=1.5 μM).
Research Areas:Cardiovascular Disease; Metabolic Disease Targets:Elastase |
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Spirorenone (INN) is a novel aldosterone antagonist with anti-salt corticosteroid activity, used in metabolic disease research.
Research Areas: Metabolic Disease Targets: Others |
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TargetMol(ターゲットモル)社について
- 本社所在地
- アメリカ マサチューセッツ州
- URL
- https://www.targetmol.com/
TargetMolは、ボストンに本社を置く低分子およびスクリーニングライブラリのサプライヤです。ライフサイエンス試薬、阻害剤、活性剤、実験用および科学用の天然化合物を提供しています。ポートフォリオには、6,000を超える化合物/阻害剤（カタログ）と80種類を超える化合物ライブラリがあります。