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MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use.
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• Over 100,000 bioactive molecules in stock
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• Target 10,000+ key proteins in 20+ signaling pathways
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• Quality reports (LC/MS, NMR and HPLC) for each product
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• Release more than 1,000 latest biochemicals per month
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• Data sheet with detailed biological information
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• High purity & competitive prices
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• Delivery within 24 hours
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CAS No.: 1869057-83-9
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Research Area: EGFR/NSCLC
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An orally active, highly brain penetrant, broadly active mutant-selective EGFR inhibitor.
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Can be used for the research of advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.
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Solubility: DMSO: 100 mg/mL (175.87 mM; Need ultrasonic)
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CAS No.: 2392951-18-5
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Research Area: Sodium Channel/Epilepsy
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An orally active sodium channel inhibitor with an anti-epileptic activity.
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Used for the research of focal onset seizures and generalized epilepsy.
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Solubility: DMSO: 175 mg/mL (430.74 mM; Need ultrasonic)
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CAS No.: 112885-41-3
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Research Area: 5-HT Receptor/Gastrointestinal Diseases
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A selective 5-HT4 receptor agonist.
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An orally active gastroprokinetic agent.
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Can be used in the study of gastrointestinal diseases.
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Solubility: DMSO: 66.67 mg/mL (158.03 mM; Need ultrasonic)
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MCE Peptides
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Structural
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Product Name
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Description
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c(avb6)-DOTA TFA
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A conjugate of an αvβ6-binding peptide and a chelator DOTA.
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CS-6253
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An ATP-binding cassette 1 (ABCA 1) agonist.
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MCE Natural Products
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Flavonoids are an important class of natural products, with antioxidant, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties, as well as the ability to regulate the function of key cellular enzymes. Flavonoids are widely used in a variety of nutritional products, medicines and cosmetics.
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Product Name
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Description
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Icariin
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A flavonol glycoside; PDE5/4 inhibitor; PPARα activator. Can be used for the study of neurological diseases.
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Puerarin
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An isoflavone; 5-HT2C receptor antagonist. Can be used for the research of rheumatoid arthritis and cardiovascular diseases.
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Catechin
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A flavanol; COX-1 inhibitor. Can be used for the research of cancer.
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Isoquercitrin
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A Flavonol; NF-κB inhibitor; NO Synthase inhibitor. Has anti-oxidant, anti-proliferative and anti-inflammatory properties.
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Baicalin
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A Flavonoside; CPT1 activator. Can be used for the study of renal.
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MCE Compound Library
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Provide professional compound library, serving cancer, immunity, metabolism and other fields of research.
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Product Name
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Description
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Methylation Compound Library
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Contains 240+ compounds targeting methylation/demethylation enzymes, which is of significant value for studying the pathways of methylation metabolism and exploring their mechanisms of action in diseases.
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Latest Publications Citing Use of MCE Products
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Nature.
2024 Nov;635(8038):472-480.
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Nature.
2024 Nov;635(8040):987-1000.
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Nature.
2024 Dec;636(8042):466-473.
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Products are for research use only and are not intended for human use. We do not sell to patients.
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