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【Medchemexpress】New Bioactive Molecules for December 2024

  • 2024/12/06
  • サプライヤニュース

新着情報一覧へ

 

MedChemExpress - Master of Bioactive Molecules (Inhibitors. Screening Libraries. Proteins)

MedChemExpress (MCE) provides a wide range of life-science biochemicals, including more than 100,000 bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. If you need these products, please do not hesitate to contact us via sales@MedChemExpress.com.

CAS No.: 1644467-84-4

OPC-163493

 

Research Area: Mitochondrial Metabolism/Reactive Oxygen Species/Diabetes

OPC-163493 structure

An orally active liver-targeted mitochondrial uncoupler.

Reduces Δψ (delta psi) and mitochondrial ROS production.

Used for the research of diabetes and ameliorates various complications of diabetes.

Solubility: DMSO: 125 mg/mL (372.79 mM; Need ultrasonic)

CAS No.: 852949-30-5

VK-0214

 

Research Area: Thyroid Hormone Receptor/X-linked Adrenoleukodystrophy

VK-0214 structure

A selective and orally active thyroid receptor-β (TRβ) agonist.

Induces the ABCD2 gene by binding to and activating the TRβ.

Used for the research of X-linked adrenoleukodystrophy (X-ALD).

Solubility: DMSO: 125 mg/mL (303.09 mM; Need ultrasonic)

CAS No.: 1948241-60-8

Ruzotolimod

 

Research Area: Toll-like Receptor (TLR)/Chronic Hepatitis B

Ruzotolimod structure

An orally active Toll-like receptor 7 (TLR7) agonist.

Can be used for the research of chronic hepatitis B (CHB).

Solubility: DMSO: 125 mg/mL (352.73 mM; Need ultrasonic)

MCE Kit

 
 

2-Color Tracking SYBR qPCR Master Mix (Universal) is a 2× concentration premixed reagent for performing SYBR Green I based quantitative PCR (qPCR).

Catalog No.

Product Name

Application

HY-K0524

2-Color Tracking SYBR qPCR Master Mix (Universal)

qPCR

Features:

1. Designed for rapid Real-Time PCR amplification, offering high repeatability and reliability.
2. Utilizes a color-changing effect from mixing distinct dyes, serving as a pipetting tracer to enhance precision.
3. Includes a unique reference dye, ensuring compatibility with a wide range of qPCR instruments without requiring additional dyes.

 

MCE Peptides

 
 

Structural

Product Name

Description

Met-RANTES (human) acetate

A CCR1 and CCR5 antagonist.

IGRP(206-214)

An IGRP fragment used to induce diabetes in non-obese diabetic (NOD) mice.

 

MCE Natural Products

 
 

Triple-negative breast cancer (TNBC) is a special subtype of breast cancer, characterized by negative estrogen receptor (ER), progesterone receptor (PR), and HER2. It has the characteristics of high invasiveness, high metastatic potential, and proneness to relapse. Natural products have anticancer and adjuvant effects in TNBC.

Product Name

Description

Hesperidin

Shows numerous biological properties, such as antitumor and antiallergic activities.

Paeonol

A MAO-A and MAO-B inhibitor that promotes anticancer effects.

Tetrandrine

A voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current inhibitor, and induces apoptosis in TNBC cell line MDA-MB-231.

Triptolide

Exhibits immunosuppressive, anti-inflammatory, antiproliferative and anti-tumor effects.

Actein

Shows an inhibitory effect on cancer cells, and induces autophagy and apoptosis of cancer cells.

 

MCE Compound Library

 
 

Provide professional compound library, serving cancer, immunity, metabolism and other fields of research.

Product Name

Description

Cell Proliferation Compound Library

Contains 2,100+ cell proliferation compounds that target and regulate key targets of cell proliferation, which can be used in studies of cell proliferation mechanisms and drug discovery.

Flavor Compound Library

Based on the FlavorDB database, this library collects and organizes 400+ flavor molecules, which can be used in taste perception and other related studies.

 

Latest Publications Citing Use of MCE Products

Covers of Recent Publications

Nature.
2024 Nov;635(8038):434-443.

Cell.
2024 Oct 31;187(22):6251-6271.e20.

Science.
2024 Sep 13;385(6714):eadj1979.

Science.
2024 Aug 30;385(6712):eado6593.

Cell Signaling Pathway

MCE USA

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Tel: +4686500910

E-mail: eu.sales@MedChemExpress.com

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Medchemexpress(メドケムエクスプレス)社について

設立
2009年
本社所在地
アメリカ
URL
http://www.medchemexpress.com/

MedChemExpress(MCE)は、新規のライフサイエンス試薬、薬理活性化合物、APIなど高品質の研究化学物質および生化学物質を幅広く提供しております。MCE のテクニカルサポートチームは経験が豊富であり、ライフサイエンス業界においては長年の経験を積んでおります。

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