Integrin α6β1 Laminin 511 は、細胞間・細胞マトリックス間の相互作用の研究において重要なタンパク質ペアで、その相互作用はさまざまな生理学的および病理学的プロセスで重要な役割を果たします。Integrin α6β1 は細胞表面受容体として、細胞外マトリックスタンパク質であるLaminin 511 に結合し、細胞の接着、移動、シグナル伝達を促進します。この相互作用は、特に腫瘍転移、組織再生、幹細胞の分化に関する研究で大きな注目を集めています。
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The Hypothetical Model of Integrin α6β1 Recognition of Laminin 5111
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Integrin α6β1 と Laminin 511 組み換えタンパク質製品は、自然な細胞マトリックス相互作用をシミュレートすることで、研究者が細胞の挙動とシグナル伝達についてより深い洞察を得るのに役立ちます。こちらの製品には、腫瘍学、再生医療、幹細胞研究などの最先端分野で幅広い応用の可能性を提供しており、科学研究や医薬品開発実験における貴重なツールとなっています。ACROBiosystems社 はIntegrin α6β1 とLaminin 511 組み換えタンパク質で、パスウェイ研究とバイオ医薬品開発のニーズを包括的にサポートしております。
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Reference:
1. Arimori, Takao & Miyazaki, Naoyuki & Mihara, Emiko & Takizawa, Mamoru & Taniguchi, Yukimasa & Cabañas, Carlos & Sekiguchi, Kiyotoshi & Takagi, Junichi. (2021). Structural mechanism of laminin recognition by integrin. Nature Communications. 12. 4012. 10.1038/s41467-021-24184-8.
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