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【TargetMol】新製品(8月版)のご紹介
- 2024/10/25
- サプライヤニュース
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| New Compound | August |
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Venuloside A (ESK246), a monoprostane glycoside from Pittosporum venulosum, is a LAT3 inhibitor and a leucine uptake inhibitor that inhibits the transporter of leucine through LAT3, and may be used in the study of prostate cancer. ).
Research Areas: Cancer Targets: Others |
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Gue1654 inhibits OXE-R-inhibited protein kinase C-ε (PKC-ε)/nuclear factor κB (NF-κB) signaling and apoptosis in cardiomyocytes. Gue1654 can be used to study cardiovascular disease.
Research Areas: Others Targets: Others |
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Ertiprotafib (PTP 112), a selective and potent inhibitor of protein tyrosine phosphate 1B (PTP1B) and IkappaB kinase β (IKK-β), is a novel insulin sensitizer with potential anticancer activity for the study of type 2 diabetes and breast cancer.
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(Rac)-Modipafantis an orally available and selective platelet-activating factor receptor (PAFR) antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits, and can be used to study arthritis and ischemia/reperfusion (I/R) in the superior mesenteric artery (SMA) of the rat.
Research Areas: Infection; Inflammation/Immunology Targets: Flavivirus; Dengue virus |
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DNL343 is a selective and potent eIF2B activator that crosses the blood-brain barrier and inhibits the assembly of stress granules (SGs) induced by the C9ORF72 dipeptide repeats. DNL343 may be useful in the study of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS).
Research Areas: Neurological Disease Targets: Eukaryotic Initiation Factor (eIF) |
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Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway.
Research Areas: Cardiovascular Disease; Cancer Targets: Reactive Oxygen Species |
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L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
Research Areas:Cardiovascular Disease Targets:Angiotensin Receptor |
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| Tel: 781-999-4286 Email: marketing@targetmolchemicals.email Add: 36 Washington Street, Wellesley Hills, MA 02481. |
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TargetMol(ターゲットモル)社について
- 本社所在地
- アメリカ マサチューセッツ州
- URL
- https://www.targetmol.com/
TargetMolは、ボストンに本社を置く低分子およびスクリーニングライブラリのサプライヤです。ライフサイエンス試薬、阻害剤、活性剤、実験用および科学用の天然化合物を提供しています。ポートフォリオには、6,000を超える化合物/阻害剤（カタログ）と80種類を超える化合物ライブラリがあります。