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【TargetMol】新製品(8月版)のご紹介

  • 2024/10/25
  • サプライヤニュース

新着情報一覧へ

 
 
Drug Screening Expert(Inhibitors,Libraries,Natural Compounds)
New Compound August
   
SPA70 Structure
Venuloside A (ESK246), a monoprostane glycoside from Pittosporum venulosum, is a LAT3 inhibitor and a leucine uptake inhibitor that inhibits the transporter of leucine through LAT3, and may be used in the study of prostate cancer. ).

Research Areas: Cancer

Targets: Others

 
 
   
Gue1654 inhibits OXE-R-inhibited protein kinase C-ε (PKC-ε)/nuclear factor κB (NF-κB) signaling and apoptosis in cardiomyocytes. Gue1654 can be used to study cardiovascular disease.

Research Areas: Others

Targets: Others
 
 
PD 198306 Chemical Structure
   
SPA70 Structure

Ertiprotafib (PTP 112), a selective and potent inhibitor of protein tyrosine phosphate 1B (PTP1B) and IkappaB kinase β (IKK-β), is a novel insulin sensitizer with potential anticancer activity for the study of type 2 diabetes and breast cancer.

Research Areas:Metabolic Disease


Targets:Phosphatase; IKK; PPAR
 
 

   
(Rac)-Modipafantis an orally available and selective platelet-activating factor receptor (PAFR) antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits, and can be used to study arthritis and ischemia/reperfusion (I/R) in the superior mesenteric artery (SMA) of the rat.

Research Areas: Infection; Inflammation/Immunology

Targets: Flavivirus; Dengue virus
 
5-HT4 antagonist 1 Chemical Structure
   
SPA70 Structure
DNL343 is a selective and potent eIF2B activator that crosses the blood-brain barrier and inhibits the assembly of stress granules (SGs) induced by the C9ORF72 dipeptide repeats. DNL343 may be useful in the study of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS).

Research Areas: Neurological Disease

Targets: Eukaryotic Initiation Factor (eIF)

 
 
   
Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium marcescens with potent antiangiogenic, anticancer and antimalarial activities. Fusarochromanone induces cell death in COS7 and HEK293 cells through activation of the JNK pathway.

Research Areas: Cardiovascular Disease; Cancer

Targets: Reactive Oxygen Species
 
5-HT4 antagonist 1 Chemical Structure
   
SPA70 Structure
L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.

Research Areas:Cardiovascular Disease

Targets:Angiotensin Receptor

 
 
   
   
Drug Screening Expert(Inhibitors,Libraries,Natural Compounds)
Tel: 781-999-4286
Email: marketing@targetmolchemicals.email
Add: 36 Washington Street, Wellesley Hills, MA 02481.
 

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