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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
VC1-H82F6
製品名称
Biotinylated Human VCAM-1 / CD106 Protein, Fc,Avitag?, premium grade
タンパク質名
VCAM-1
Species
Human
HOST
HEK293
25ug: 98000円
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200ug: 386400円
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Overview

Synonyms -
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 102.4 kDa. The protein migrates as 130 kDa±5 kDa under reducing (R) condition, and >250 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 0.01 EU per μg
Purity 95%
Description Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.
Reference -
URL https://www.acrobiosystems.com/P5465-Biotinylated-Human-VCAM-1--CD106-Protein-FcAvitag%E2%84%A2-premium-grade.html

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