Biotinylated Cynomolgus VCAM-1 / CD106 Protein, His,Avitag? (MALS verified) [VC1-C82E3]

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サプライヤー: AcroBioSystems
カタログNo.: VC1-C82E3
製品名称: Biotinylated Cynomolgus VCAM-1 / CD106 Protein, His,Avitag? (MALS verified)
タンパク質名: VCAM-1
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 77.8 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/vcam-1-cynomolgus-vc1-c82e3

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