検索リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト：Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- TOA-H5117
- 製品名称
- Human TOP2A / TOP2 Protein, Tag Free
- タンパク質名
- TOP2A
- Species
- Human
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries no "tag". The protein has a calculated MW of 12.8 kDa. The protein migrates as 20 kDa under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations. |
| Reference | - |
| URL | https://www.acrobiosystems.com/P3463-Human-TOP2A--TOP2-Protein-Tag-Free.html |
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