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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-06986
- 製品名称
- FGF-8b Protein, Human, Recombinant
- タンパク質名
- FGF-8b
- Species
- Human
- HOST
- E. coli
- 50μg: -
- お問い合わせ
Overview
| Synonyms | NEWENTRY, fibroblast growth factor 8 (androgen-induced), FGF-8, KAL6, AIGF, HH6, HBGF-8 |
|---|---|
| Characteristics | Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50?for this effect is typically 0.4-1.6 μg/mL. |
| Endotoxin Level | Please contact us for more information. |
| Purity | 94.30% |
| Description | In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/recombinant_human_fgf_8b_fgf8b_protein |
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