GDNF Protein, Human, Recombinant [TMPY-06970]

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Synonyms	ATF1, ATF2, glial cell derived neurotrophic factor, HSCR3, HFB1-GDNF
Characteristics	Measured in a cell proliferation assay using SH?SY5Y human neuroblastoma cells. The ED50 for this effect is typically 1-5 ng/mL in the presence of Recombinant Human GFR alpha?1/GDNF R alpha?1 His Chimera.
Endotoxin Level	< 10 EU/mg of the protein.
Purity	? 95 % as determined by SDS-PAGE
Description	GDNF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P39905-1.
Reference	Oppenheim RW,et al. (1995) Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature. 373 (6512): 344-6.,Tomac A,et al. (1995) Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature. 373 (6512): 335-9.,Genomics. 28 (3): 605-7.Carnicella S,et al. (2008) GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc Natl Acad Sci . 105 (23): 8114-9.,Schindelhauer D,et al. (1996) The gene coding for glial cell line derived neurotrophic factor (GDNF) maps to chromosome 5p12-p13.1.
URL	https://www.targetmol.com/recombinant-protein/gdnf_protein_human_recombinant_hplc_verified

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