KRAS Protein, Human, Recombinant (G12D, His) [TMPY-06056]

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Synonyms	KRAS1, K-RAS4B, Kirsten rat sarcoma viral oncogene homolog, RALD, C-K-RAS, K-RAS2B, K-RAS2A, K-RAS, KI-RAS, NS, KRAS2, RASK2, NS3, CFC2, K-RAS4A
Characteristics	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	92.50%
Description	KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
Reference	Matallanas D,et al.(2011) Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. Mol Cell. 44(6):893-906.,Regala RP,et al.(2011) Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation. PLoS One. 6(10):e26439.,Ling J,et al.(2012) KrasG12D-induced IKK2//NF-B activation by IL-1 alpha and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 21(1):105-20.
URL	https://www.targetmol.com/recombinant-protein/kras_protein_human_recombinant_his_tag_

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