FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) [TMPY-06036]

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Synonyms	OGD, FGFR1 α (IIIc), FGFR-1, FLG, CD331, HH2, FLT2, KAL2, FGFBR, HBGFR, CEK, HRTFDS, fibroblast growth factor receptor 1, N-SAM, bFGF-R-1, FLT-2, BFGFR
Characteristics	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	99.50%
Description	FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
Reference	Dod? C,et al.(2007) Novel FGFR1 sequence variants in Kallmann syndrome, and genetic evidence that the FGFR1c isoform is required in olfactory bulb and palate morphogenesis. Hum Mutat. 28(1): 97-8.,Kim HG,et al.(2005) Hypogonadotropic hypogonadism and cleft lip and palate caused by a balanced translocation producing haploinsufficiency for FGFR1. J Med Genet. 42(8):666-72.,Schlessinger J,et al.(2000) Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell. 6(3):743-50.
URL	https://www.targetmol.com/recombinant-protein/fgfr1_protein_human_recombinant_alpha_iiib_his_tag_

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