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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-05791
- 製品名称
- CD155/PVR Protein, Mouse, Recombinant (mFc)
- タンパク質名
- CD155/PVR
- Species
- Mouse
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | Taa1, 3830421F03Rik, poliovirus receptor, necl-5, D7Ertd458e, HVED, CD155, PVS, mE4, Tage4 |
|---|---|
| Characteristics | 1. Measured by its binding ability in a functional ELISA. Immobilized TIGIT Protein, Human, Recombinant (ECD, His Tag) at 2 μg/ml (100 μl/well) can bind CD155/PVR Protein, Mouse, Recombinant (mFc Tag), the EC50 of CD155/PVR Protein, Mouse, Recombinant (mFc Tag) is 25-140 ng/mL. 2. Immobilized mouse CD155 (mFc Tag) at 2 μg/mL (100μL/well) can bind Mouse TIGIT-His, HPLC-verified, the EC50 of Mouse TIGIT-His, HPLC-verified is 300-900 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 95.2%; SEC-HPLC: 95.8% |
| Description | CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094. |
| Reference | Freistadt MS, et al. (2000) Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo. Microb Pathog. 29(4): 203-12.,Kakunaga S, et al. (2004) Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. 279(35): 36419-25.,Sato T, et al. (2004) Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions. Genes Cells. 9(9): 791-9.,Sato T, et al. (2005) Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion. Cancer Sci. 96(9): 578-89.,Minami Y, et al. (2007) Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells. Biochem Biophys Res Commun. 352(4): 856-60. |
| URL | https://www.targetmol.com/recombinant-protein/cd155_pvr_protein_mouse_recombinant_mfc_tag_ |
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