4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) [TMPY-05767]

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Synonyms	4-1BB, Cd137, AI325004, A930040I11Rik, Ly63, ILA, tumor necrosis factor receptor superfamily, member 9, AA408498, CDw137
Characteristics	Measured by its binding ability in a functional ELISA. Immobilized Rat 4-1BBL/TNFSF9 hFc at 2 μg/ml (100 μl/well) can bind Mouse CD137 His, the EC50 of Mouse CD137 His is 0.7-4.2 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	90.60%
Description	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.00 kDa and the accession number is P20334.
Reference	Sica G,et al.(1999) Biochemical and immunological characteristics of 4-1BB (CD137) receptor and ligand and potential applications in cancer therapy. Arch Immunol Ther Exp (Warsz). 47(5): 275-9.,Thum E,et al.(2009) CD137, implications in immunity and potential for therapy. Front Biosci. 14: 4173-88.,Wang Q,et al.(2008) Analysis of CD137 and CD137L expression in human primary tumor tissues. Croat Med J. 49(2): 192-200.,Melero I,et al.(2008) Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies. Trends Pharmacol Sci. 29(8): 383-90.,Nam KO,et al.(2005)?The therapeutic potential of 4-1BB (CD137) in cancer.?Curr Cancer Drug Targets. 5(5): 357-63.
URL	https://www.targetmol.com/recombinant-protein/4_1bb_cd137_protein_mouse_recombinant_ecd_his_tag_

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