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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-05480
- 製品名称
- IL-21R Protein, Human, Recombinant (hFc)
- タンパク質名
- IL-21R
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
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Overview
| Synonyms | interleukin 21 receptor, CD360, NILR |
|---|---|
| Characteristics | 1. Measured by its ability to inhibit IL21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 40-200 ng/mL in the presence of 2 ng/mL of recombinant human IL21. 2. Immobilized Recombinant Human Interleukin-21 / IL-21 Protein at 2μg/mL (100μL/well) can bind Recombinant Human IL-21R / Il21R Protein (Fc Tag), the EC50 is 130-480 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 92.30% |
| Description | IL-21R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9HBE5. |
| Reference | Wu Z, et al. (2005) Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity. Mol Cell Biol. 25(22): 9741-52.,Asao H, et al. (2001) Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol. 167(1): 1-5.,De Totero D, et al. (2006) Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells. Blood. 107(9): 3708-15. |
| URL | https://www.targetmol.com/recombinant-protein/il21_receptor_protein_human_recombinant_hfc_tag_ |
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