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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-05260
- 製品名称
- PD-1 Protein, Cynomolgus, Recombinant (His)
- タンパク質名
- PD-1
- Species
- Cynomolgus
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | programmed cell death 1 |
|---|---|
| Characteristics | 1. Immobilized PD-1 Protein, Cynomolgus, Recombinant (His Tag) at 2 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus PD-L1 / B7-H1 / CD274 Protein (Fc Tag), the EC50 is 16-86 ng/mL. 2. Immobilized PD-1 Protein, Cynomolgus, Recombinant (His Tag) at 2 μg/mL (100 μL/well) can bind Anti-PD1(MDX)-IgG4 Antibody (Nivolumab), the EC50 is 6-40 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98.80% |
| Description | PD-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is B0LAJ3. |
| Reference | Riley JL.(2009) PD-1 signaling in primary T cells. Immunol Rev. 229(1): 114-25.,Okazaki T, et al. (2007) PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 19(7): 813-24.,James ES, et al. (2005) PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders. Genes Immun. 6(5): 430-7.,del Rio ML, et al. (2008) PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation. Transpl Int. 21(11): 1015-28. |
| URL | https://www.targetmol.com/recombinant-protein/pd_1_protein_cynomolgus_recombinant_his_tag_hplc_verified |
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