CD122/IL2RB Protein, Human, Recombinant (His) [TMPY-05216]

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Synonyms	IL-15RB, interleukin 2 receptor, β, P70-75, IL15RB, interleukin 2 receptor, beta, CD122
Characteristics	Measured by its ability to inhibit IL15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4.0 ng/mL of recombinant human IL-15. The ED50 for this effect is 0.4-3μg/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 98.9%; SEC-HPLC: 94.3%
Description	CD122/IL2RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P14784.
Reference	Foss F. (2006) Clinical experience with denileukin diftitox (ONTAK). Semin Oncol. 33(1 Suppl 3): 11-6.,Sprent J, et al. (2001) T cell death and memory. Science. 293(5528): 245-8.,Teshigawara K, et al. (1987) Interleukin 2 high-affinity receptor expression requires two distinct binding proteins. J Exp Med. 165 (1): 223-38.
URL	https://www.targetmol.com/recombinant-protein/cd122_il2rb_protein_human_recombinant_ecd_his_tag_hplc_verified

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