TGFBR2 Protein, Human, Recombinant (His) [TMPY-05157]

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Synonyms	LDS2B, FAA3, TAAD2, MFS2, TGFR-2, TGFbeta-RII, transforming growth factor, beta receptor II (70/80kDa), LDS2, transforming growth factor, β receptor II, LDS1B, AAT3, TGFβ-RII, RIIC
Characteristics	Measured by its binding ability in a functional ELISA.?Immobilized TGFBR2h (1-166Q) at 10 μg/mL (100 μL/well) can bind TGFB1-His/Biotin , the EC50 of human TGFB1-His/Biotin is 130-300 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	89.30%
Description	TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
Reference	Biros E,et al.(2011) Meta-analysis of the association between single nucleotide polymorphisms in TGF-β receptor genes and abdominal aortic aneurysm. Atherosclerosis. 219(1):218-23.,Shima K,et al.(2011) TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers. PLoS One. 6(9):e25062.,Yu Y,et al.(2012) MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFβR2) in colon cancer cells. Carcinogenesis. 33(1):68-76.
URL	https://www.targetmol.com/recombinant-protein/tgfbr2_protein_human_recombinant_ecd_his_tag_

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