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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04957
- 製品名称
- PD-L2 Protein, Human, Recombinant (His), Biotinylated
- タンパク質名
- PD-L2
- Species
- Human
- HOST
- HEK293 Cells
- 20μg: -
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Overview
| Synonyms | PDCD1L2, PDL2, programmed cell death 1 ligand 2, B7DC, Btdc, B7-DC, bA574F11.2, PD-L2, CD273 |
|---|---|
| Characteristics | Measured by its binding ability in a functional ELISA. Immobilized Human PD-1 hFc at 2 μg/ml (100 μl/well) can bind Human PD-L2 His, Biotinylated, the EC50 of Human PD-L2 His, Biotinylated is 300-900 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98.50% |
| Description | PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. |
| Reference | Latchman Y,et al.(2001) PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol. 2: 261-8.,Radhakrishnan S,et al.(2007) B7-DC/PD-L2 cross-linking induces NF-kappaB-dependent protection of dendritic cells from cell death. J Immunol. 178(3): 1426-32.,Carreno BM,et al.(2005) Therapeutic opportunities in the B7/CD28 family of ligands and receptors. Curr Opin Pharmacol. 5(4): 424-30. |
| URL | https://www.targetmol.com/recombinant-protein/pd_l2_protein_human_recombinant_his_tag_biotinylated |
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