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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04949
- 製品名称
- PD-L1 Protein, Human, Recombinant (His), Biotinylated
- タンパク質名
- PD-L1
- Species
- Human
- HOST
- HEK293 Cells
- 20μg: -
- お問い合わせ
Overview
| Synonyms | PDCD1LG1, B7H1, PD-L1, B7-H1, B7-H, CD274 molecule, PDL1, PDCD1L1 |
|---|---|
| Characteristics | Measured by its binding ability in a functional ELISA. Immobilized Human PD-1 His & hFc at 2 μg/ml (100 μl/well) can bind Human PD-L1 His, Biotinylated, the EC50 of Human PD-L1 His, Biotinylated is 50-300 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98% |
| Description | PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1. |
| Reference | Wilcox RA, et al. (2009) B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders. Blood. 114(10): 2149-58.,Ghebeh H, et al. (2006) The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors. Neoplasia. 8(3): 190-8.,Salih HR, et al. (2006) The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans. Exp Hematol. 34(7): 888-94.,Ruggiero A, et al. (2009) Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. leaves with the property to induce DNA cleavage. Biopolymers. 91(12): 1135-42.,Iwai Y, et al. (2002) Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A. 99(19): 12293-7. |
| URL | https://www.targetmol.com/recombinant-protein/pd_l1_protein_human_recombinant_ecd_his_tag_biotinylated |
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