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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04911
- 製品名称
- VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
- タンパク質名
- VEGF165
- Species
- Human,Cynomolgus
- HOST
- HEK293 Cells
- 20μg: -
- お問い合わせ
Overview
| Synonyms | vascular endothelial growth factor A |
|---|---|
| Characteristics | 1.Measured in a cell proliferation assay using human, Cynomolgus umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 4-16 ng/mL. 2.Loaded Avastin on ProA Biosensor, can bind Biotinylated Human, Cynomolgus VEGF protein, His & AVI Tag with an affinity constant of 0.443nM as determined in BLI assay (Routinely tested). |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98.10% |
| Description | VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4. |
| Reference | Jia SF,et al.(2008) VEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cells. J Exp Ther Oncol. 7(2): 89-97.,Woolard J.et al.(2004) VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Res. 64(21): 7822-7835.,Cimpean AM,et al.(2008) Vascular endothelial growth factor A (VEGF A) as individual prognostic factor in invasive breast carcinoma. Rom J Morphol Embryol. 49(3): 303-8.,Eisenach PA,et al.(2010) MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 123(Pt 23):4182-4193.,Claesson-Welsh L (2010) Gremlin: vexing VEGF receptor agonist. Blood. 116(18):3386-7.,HAmdollah Zadeh MA,et al.(2008) VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6. Microcirculation. 15(7): 605-14. |
| URL | https://www.targetmol.com/recombinant-protein/vegf165_protein_human_recombinant_his_avi_tag_biotinylated |
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