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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04898
- 製品名称
- PD-1 Protein, Human, Recombinant (hFc)
- タンパク質名
- PD-1
- Species
- Human
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | PD1, programmed cell death 1, PD-1, hPD-l, hSLE1, CD279, hPD-1, SLEB2 |
|---|---|
| Characteristics | 1. Measured by its ability to bind Biotinylated?Human PD-L1-His ?in a functional ELISA.<br> 2. Measured by its ability to bind Biotinylated?Human PD-L2-His ?in a functional ELISA.<br> 3. Immobilized PD-1 Protein, Human, Recombinant (ECD, hFc Tag) at 2 μg/mL (100 μL/well) can bind PD-L2 Protein, Human, Recombinant (ECD, His Tag) , the EC50 is 45-280 ng/mL.<br> 4. Labeled biotin to PD-1 Protein, Human, Recombinant (Fc Tag) by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of PD-1 Protein, Human, Recombinant (Fc Tag), Biotinylated bound to Atezolizumab was 0.3 nM. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 92.4%; SEC-HPLC: 92.8% |
| Description | PD-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A0M3M0G7. |
| Reference | del Rio ML, et al. (2008) PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation. Transpl Int. 21(11): 1015-28.,Okazaki T, et al. (2007) PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 19(7): 813-24.,Riley JL.(2009) PD-1 signaling in primary T cells. Immunol Rev. 229(1): 114-25.,James ES, et al. (2005) PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders. Genes Immun. 6(5): 430-7. |
| URL | https://www.targetmol.com/recombinant-protein/pd_1_protein_human_recombinant_ecd_hfc_tag_hplc_verified |
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