ALK-2/ACVR1 Protein, Human, Recombinant (His) [TMPY-04774]

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Synonyms	TSRI, ACVRLK2, FOP, activin A receptor, type I, ACTRI, ACVR1A, SKR1, ALK2
Characteristics	Kinase activity untested
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	96.90%
Description	ALK-2/ACVR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.8kDa and the accession number is Q04771.
Reference	Armes NA, et al. (1999) A short loop on the ALK-2 and ALK-4 activin receptors regulates signaling specificity but cannot account for all their effects on early Xenopus development. J Biol Chem. 274(12):7929-35.,Kawai S, et al. (2000) Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity.Biochem Biophys Res Commun. 271(3):682-7.,Deng Y, et al. (2009) Efficient highly selective synthesis of methyl 2-(ethynyl)alk-2(E)-enoates and 2-(1'-chlorovinyl)alk-2(Z)-enoates from 2-(methoxycarbonyl)-2,3-allenols. Organic letters 11(10):2169-72.,Armes NA, et al. (1997) The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds. Development 124(19): 3797-804.
URL	https://www.targetmol.com/recombinant-protein/acvr1_protein_human_recombinant_his_tag_

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