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サプライヤー
TargteMol
カタログNo.
TMPY-04730
製品名称
LAG-3 Protein, Human, Recombinant (His)
タンパク質名
LAG-3
Species
Human
HOST
HEK293 Cells
50μg: -
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Overview

Synonyms LAG-3, lymphocyte-activation gene 3, CD223
Characteristics 1. Immobilized LAG3 Protein, Human, Recombinant (ECD, His Tag) at 2 μg/mL (100 μL/well) can bind Anti-LAG3(BMS)-IgG4 Antibody (Relatlimab), the EC50 is 8-40 ng/mL.
2.Captured Anti-LAG3 Mab (Human IgG4) on proA Chip can bind LAG3 with an affinity?constant of 88.45 pM as determined in a SPR assay(Routinely tested) .
3.Loaded Anti-LAG-3 Mab(Human IgG4) on ProA Biosensor, can bind human LAG-3 protein, His Tag with an affinity constant of 0.617nM as determined in BLI assay (Routinely tested).
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 98.50%
Description LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number is P18627-1.
Reference Triebel F. et al., 1990, J Exp Med. 171 (5): 1393-405.,Huard B. et al., 1997, Proc Natl Acad Sci. 94 (11): 5744-9.,Sigrid Hannier. et al., 1998, The Journal of Immunology. 161(8): 4058-65.,Baixeras E. et al., 1992, J Exp Med. 176 (2): 327-37.,Kisielow M. et al., 2005, Eur J Immunol. 35 (7): 2081-8.
URL https://www.targetmol.com/recombinant-protein/lag3_protein_human_recombinant_ecd_his_tag_hplc_verified

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