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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04722
- 製品名称
- DcR1/TRAILR3 Protein, Human, Recombinant (His)
- タンパク質名
- DcR1/TRAILR3
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | TRAILR3, TRID, DCR1, TRAIL-R3, CD263, DCR1-TNFR, tumor necrosis factor receptor superfamily member 10c, LIT |
|---|---|
| Characteristics | 1.Measured by its binding ability in a functional ELISA. 2. Immobilized human TNFRSF10C at 10μg/mL (100μL/well) can bind biotinylated human TNFSF10 (10409-HNAE), the EC50 of biotinylated human TNFSF10 is 0.1-0.7μg/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 97.50% |
| Description | TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/dcr1_trailr3_protein_human_recombinant_his_tag_ |
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