CD122/IL2RB Protein, Rhesus, Recombinant (His) [TMPY-04717]

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Synonyms	interleukin 2 receptor, β, interleukin 2 receptor, beta
Characteristics	Measured by its ability to inhibit IL-15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4 ng/mL of recombinant human IL-15. The ED50 for this effect is typically 0.2-1.2 μg/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 99.3%; SEC-HPLC: 96.7%
Description	CD122/IL2RB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.1 kDa and the accession number is H9Z8K1.
Reference	Foss F. (2006) Clinical experience with denileukin diftitox (ONTAK). Semin Oncol. 33(1 Suppl 3): 11-6.,Teshigawara K, et al. (1987) Interleukin 2 high-affinity receptor expression requires two distinct binding proteins. J Exp Med. 165 (1): 223-38.,Sprent J, et al. (2001) T cell death and memory. Science. 293(5528): 245-8.
URL	https://www.targetmol.com/recombinant-protein/cd122_il2rb_protein_rhesus_recombinant_his_tag_

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