MKK4 Protein, Mouse, Recombinant (His & GST) [TMPY-04572]

輸入に関する法規制チェックは、御見積のご依頼をいただいた際に行います。
法規制によっては、定価として記載の価格に追加の費用が発生する場合や供給出来ない場合がございますので、あらかじめご了承ください。

Synonyms	MKK4, MEK4, PRKMK4, Sek1, JNKK1, Serk1, mitogen-activated protein kinase kinase 4
Characteristics	No Kinase Activity
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	81.90%
Description	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / JNKK1 has been shown to activate MAPK8 / JNK1, MAPK9 / JNK2, and MAPK14 / p38, but not MAPK1 / ERK2 or MAPK3 / ERK1. MAP2K4 / JNKK1 is phosphorylated, and thus activated by MAP3K1 / MEKK. The stress-activated protein kinase (SAPK) pathways represent phosphorylation cascades that convey pro-apoptotic signals. The mitogen-activated protein kinase kinase (MAPKK) homolog MAP2K4 ( MKK4, SEK, JNKK1 ) is a centrally-placed mediator of the SAPK pathways.
Reference	Lin A, et al.,1995, Science?268?(5208): 286-90.,Su,G.H. et al., 2002, Hum Mutat. 19?(1):81.,Lee, et al., 2002, Proc. Natl. Acad. Sci. USA. 99?(22): 14189-94.,Bouzakri,K. et al., 2007,?J Biol Chem. 282?(11):7783-9.
URL	https://www.targetmol.com/recombinant-protein/mkk4_protein_mouse_recombinant_his_gst_tag_

バイオ製品Bio Products