PKM2 Protein, Human, Recombinant (His) [TMPY-04465]

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Synonyms	pyruvate kinase, muscle, OIP3, CTHBP, PK3, THBP1, HEL-S-30, TCB, PKM2
Characteristics	Kinase activity untested
Endotoxin Level	Please contact us for more information.
Purity	> 90 % as determined by SDS-PAGE
Description	PKM2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 59 kDa and the accession number is P14618-1.
Reference	Gupta V, et al. (2010) Dominant Negative Mutations Affect Oligomerization of Human Pyruvate Kinase M2 Isozyme and Promote Cellular Growth and Polyploidy. J Biol Chem. 285 (22): 16864-73.,Eigenbrodt E, et al. (1992) Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells. Crit Rev Oncog. 3 (1): 91-115.,Bluemlein K, et al. (2011) No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis. Oncotarget. 2 (5): 393-400.
URL	https://www.targetmol.com/recombinant-protein/pkm2_protein_human_recombinant_his_tag_

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