タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04346
- 製品名称
- PD-L2 Protein, Human, Recombinant (His)
- タンパク質名
- PD-L2
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | PD-L2, B7-DC, CD273, Btdc, PDCD1L2, B7DC, PDL2, programmed cell death 1 ligand 2, bA574F11.2 |
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Characteristics | Measured by its binding ability in a functional ELISA. Immobilized human PD-L2 at 2 μg/ml (100 μl/well) can bind human PD-1 , the EC50 of human PD-1 is 150-800 ng/mL. |
Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity | SDS-PAGE: 98.2%; SEC-HPLC: 91.2% |
Description | PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. |
Reference | Latchman Y,et al.(2001) PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol. 2: 261-8.,Radhakrishnan S,et al.(2007) B7-DC/PD-L2 cross-linking induces NF-kappaB-dependent protection of dendritic cells from cell death. J Immunol. 178(3): 1426-32.,Carreno BM,et al.(2005) Therapeutic opportunities in the B7/CD28 family of ligands and receptors. Curr Opin Pharmacol. 5(4): 424-30. |
URL | https://www.targetmol.com/recombinant-protein/pd_l2_protein_human_recombinant_ecd_his_tag_hplc_verified |