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サプライヤー
TargteMol
カタログNo.
TMPY-04332
製品名称
IL-17A Protein, Human, Recombinant (T26A, His)
タンパク質名
IL-17A
Species
Human
HOST
Baculovirus Insect Cells
100μg: -
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Overview

Synonyms CTLA-8, CTLA8, IL-17A, interleukin 17A, IL17, IL-17
Characteristics Measured by its ability to induce IL-6 secretion by NIH?3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.5-2.5 ng/mL.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity > 95 % as determined by SDS-PAGE
Description IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552.
Reference Andoh A, et al. (2002) IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. J Immunol. 169(4):1683-7.,Shin HC, et al. (1999) Regulation of IL-17, IFN-gamma and IL-10 in human CD8(+) T cells by cyclic AMP-dependent signal transduction pathway. Cytokine. 10(11):841-50.,Laan M, et al. (1999) Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol. 162(4):2347-52.,Kotake S, et al. (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest. 103(9):1345-52.
URL https://www.targetmol.com/recombinant-protein/il17_protein_human_recombinant_t26a_his_tag_

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