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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04329
- 製品名称
- Vimentin Protein, Human, Recombinant (His)
- タンパク質名
- Vimentin
- Species
- Human
- HOST
- Baculovirus Insect Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | CTRCT30, HEL113, vimentin |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 93.30% |
| Description | Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. Therefore, in general, it is accepted that vimentin is the cytoskeletal component responsible for maintaining cell integrity. Vimentin is also responsible for stabilizing cytoskeletal interactions. It is found that vimentin control the transport of low-density lipoprotein. It has been used as a sarcoma tumor marker to identify mesenchyme. |
| Reference | Russell SM,et al.(1993) Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science. 262 (5141): 1880-3.,Miyazaki T,et al.(1994) Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science. 266 (5187): 1045-7.,Takeshita T,et al.(1992) Cloning of the gamma chain of the human IL-2 receptor. Science. 257 (5068): 379-82. |
| URL | https://www.targetmol.com/recombinant-protein/vimentin_protein_human_recombinant_his_tag_ |
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