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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-04261
- 製品名称
- CD64 Protein, Human, Recombinant (His)
- タンパク質名
- CD64
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | CD64, Fc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI |
|---|---|
| Characteristics | 1. Immobilized Anti-CD20(Ro) Antibody (Rituximab) at 1 μg/mL (100 μL/well) can bind Recombinant Human CD64/FCGR1A Protein (His Tag), the EC50 is 0.6-2.0 ng/mL.<br> 2. Captured Human FcγRI/CD64 recombinant protein on?Anti-His?Chip?can?bind?Bevacizumab (IgG1) with?an?affinity?constant of 5.5?nM?as?determined in an?SPR assay.<br> 3. Captured Human FcγRI/CD64 recombinant protein on?Anti-His?Chip?can?bind?Nivolumab (IgG4) with?an?affinity?constant of 13.6 nM?as determined in an?SPR assay.<br> 4. Loaded Human FcγRI / CD64 recombinant protein on His1K Biosensor, can bind Nivolumab (IgG4) with an affinity constant of 8.5 nM as determined in a BLI assay.<br> 5. Loaded Human FcγRI / CD64 recombinant protein on His1K Biosensor, can bind Bevacizumab (IgG1) with an affinity constant of 4.7 nM as determined in a BLI assay.<br> 6. Loaded Rituximab (IgG1) on ProA Biosensor, can bind Human FcγRI/CD64 recombinant protein with an affinity constant of 0.38 nM as determined in a BLI assay.<br> 7. The purity of Human CD64/FCGR1A Protein (His Tag) is more than 95% and the molecular weight of this protein is around 38-52 kDa verified by SEC-MALS. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 98.9%; SEC-HPLC: 96.4% |
| Description | CD64 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is P12314-1. |
| Reference | Allen J.M., et al.,(1988), Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI). Nucleic Acids Res. 16:11824-11824.,Porges A.J., et al.,(1992), Novel Fc gamma receptor I family gene products in human mononuclear cells.J. Clin. Invest. 90:2102-2109.,Allen J.M., et al., (1989), Isolation and expression of functional high-affinity Fc receptor complementary DNAs.Science 243:378-381. |
| URL | https://www.targetmol.com/recombinant-protein/cd64_protein_human_recombinant_ecd_his_tag_hplc_verified |
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