IL-17RB Protein, Human, Recombinant (His) [TMPY-04052]

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Synonyms	interleukin 17 receptor B, CRL4, IL17BR, EVI27, IL17RH1
Characteristics	Measured by its binding ability in a functional ELISA. Immobilized human IL17BR-His at 10 μg/ml (100 μl/well) can bind human Fc-IL25 , The EC50 of human Fc-IL25 is 0.1-0.3 μg/ml.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 98.4%; SEC-HPLC: 99.0%
Description	IL-17RB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number is Q9NRM6-1.
Reference	Stock P,et al.. (2009) Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J Immunol. 182(8): 5116-22.,Rickel EA,et al.. (2008) Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol. 181(6): 4299-310.,Wang H,et al.. (2010) Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation. Clin Exp Allergy. 40(8): 1194-202.
URL	https://www.targetmol.com/recombinant-protein/il17rb_protein_human_recombinant_his_tag_hplc_verified

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