c-Kit Protein, Human, Recombinant (hFc) [TMPY-04051]

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Synonyms	SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PBT, CD117, C-Kit
Characteristics	Immobilized Human SCF His at 2 μg/ml (100 μl/well) can bind Human c-Kit hFc , the EC50 of Human c-Kit hFc is 20-60 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	97.10%
Description	c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
Reference	Yarden Y, et al. (1987) Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J. 6(11):3341-51.,Andre C, et al. (1997) Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes. Genomics. 39(2):216-26.,Leong KG, et al. (2008) Generation of a prostate from a single adult stem cell. Nature. 456(7223): 804-8.,McIntyre A, et al. (2005) Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults. Cancer Res. 65(18):8085-9.,Edling CE, et al. (2007) c-Kit--a hematopoietic cell essential receptor tyrosine kinase. Int J Biochem Cell Biol. 39(11):1995-8.
URL	https://www.targetmol.com/recombinant-protein/c_kit_protein_human_recombinant_hfc_tag_

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