T Plastin/PLS3 Protein, Human, Recombinant (His) [TMPY-03987]

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Synonyms	BMND18, T-plastin, plastin 3
Characteristics	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	Please contact us for more information.
Purity	> 95 % as determined by SDS-PAGE
Description	PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). PLS3 contains 2 actin-binding domains, 4 CH (calponin-homology) domains and 2 EF-hand domains. It is expressed in a variety of organs, including muscle, brain, uterus and esophagus.
Reference	Lin CS. et al., 1993, J Biol Chem 268 (4): 2781-92.,Arpin M. et al., 1995, J Cell Biol. 127 (2): 1995-2008.,Goldstein D. et al., 1985, Cancer Res. 45 (2): 5643-7.
URL	https://www.targetmol.com/recombinant-protein/t_plastin_pls3_protein_human_recombinant_his_tag_

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