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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03958
- 製品名称
- TGF alpha Protein, Human, Recombinant
- タンパク質名
- TGF alpha
- Species
- Human
- HOST
- E. coli
- 20μg: -
- お問い合わせ
Overview
| Synonyms | transforming growth factor α, TGFa, TGF-α, transforming growth factor alpha, TFGA |
|---|---|
| Characteristics | 1.Measured by its binding ability in a functional ELISA. Immobilized Human TGF-alpha at 2 μg/ml (100 μl/well) can bind Human EGFR hFc, the EC50 of Human EGFR hFc is 80-500 ng/mL. 2. Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.5-2.5 ng/mL. |
| Endotoxin Level | Please contact us for more information. |
| Purity | 94.90% |
| Description | The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P). |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/tgf_alpha_protein_human_recombinant |
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