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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03956
- 製品名称
- Fas Ligand Protein, Human, Recombinant (His)
- タンパク質名
- Fas Ligand
- Species
- Human
- HOST
- P. pastoris (Yeast)
- 50μg: -
- お問い合わせ
Overview
| Synonyms | FASL, FASLG, CD178, CD95-L, APT1LG1, APTL, CD95L, Fas ligand, ALPS1B, TNFSF6, TNLG1A |
|---|---|
| Characteristics | Immobilized Human Fas/CD95 hFc at 2 μg/mL (100 μL/well) can bind Human Fas Ligand His , the EC50 of Human Fas Ligand His is 40-200 ng/mL. |
| Endotoxin Level | Please contact us for more information. |
| Purity | SDS-PAGE: > 90% |
| Description | Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 19.3 kDa and the accession number is P48023-1. |
| Reference | Pitti R M. et al., 1998, Nature. 396 (6712): 699-703.,HAne M. et al., 1995, FEBS Lett. 373 (3): 265-8.,Schneider P. et al., 1997, J Biol Chem. 272 (30): 18827-33. |
| URL | https://www.targetmol.com/recombinant-protein/fas_ligand_protein_human_recombinant_his_tag_ |
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