E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) [TMPY-03762]

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Synonyms	cadherin 1, type 1, E-cadherin (epithelial), Arc-1, E-Cadherin, UVO, CDHE, CD324, ECAD, CDH1, E-cad, LCAM
Characteristics	Measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast adenocarcinoma cells. When cells are added to E-Cad coated plates (5 μg/mL, 100 μL/well), > 30% will adhere specifically after 90 minutes at 37 ℃.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 90.3%; SEC-HPLC: 95.0%
Description	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.1 kDa and the accession number is P12830-1.
Reference	Mrgineanu E,et al.(2008) Correlation between E-cadherin abnormal expressions in different types of cancer and the process of metastasis. Rev Med Chir Soc Med Nat Iasi. 112(2): 432-6.,Wang HD,et al.(2004) CDH1 germline mutation in hereditary gastric carcinoma. World J Gastroenterol. 10(21): 3088-93.,Masterson J,et al.(2007) Posttranslational truncation of E-cadherin and significance for tumour progression. Cells Tissues Organs. 185(1-3): 175-9.
URL	https://www.targetmol.com/recombinant-protein/e_cadherin_protein_human_recombinant_ecd_hfc_tag_

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