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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03698
- 製品名称
- VEGF121b Protein, Human, Recombinant
- タンパク質名
- VEGF121b
- Species
- Human
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
| Synonyms | MVCD1, VEGF, VPF, vascular endothelial growth factor A |
|---|---|
| Characteristics | 1. Measured by its binding ability in a functional ELISA. Immobilized human VEGF121b at 10μg/mL (100μL/well) can bind human VEGFR2-Fc, the EC50 of human VEGFR2-Fc is 0.06-0.1 μg/mL. 2. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 1-5ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 97.70% |
| Description | VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9. |
| Reference | Jia SF,et al.(2008) VEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cells. J Exp Ther Oncol. 7(2): 89-97.,Woolard J.et al.(2004) VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Res. 64(21): 7822-7835.,Eisenach PA,et al.(2010) MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 123(Pt 23):4182-4193.Claesson-Welsh L (2010) Gremlin: vexing VEGF receptor agonist. Blood. 116(18):3386-7.,HAmdollah Zadeh MA,et al.(2008) VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6. Microcirculation. 15(7): 605-14.,Cimpean AM,et al.(2008) Vascular endothelial growth factor A (VEGF A) as individual prognostic factor in invasive breast carcinoma. Rom J Morphol Embryol. 49(3): 303-8. |
| URL | https://www.targetmol.com/recombinant-protein/vegf121b_protein_human_recombinant |
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