タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03672
- 製品名称
- Survivin Protein, Human, Recombinant
- タンパク質名
- Survivin
- Species
- Human
- HOST
- E. coli
- 100μg: -
- お問い合わせ
Overview
Synonyms | API4, baculoviral IAP repeat containing 5, EPR-1, BIRC5, IAP4 |
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Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Endotoxin Level | Please contact us for more information. |
Purity | > 95 % as determined by SDS-PAGE |
Description | BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase. |
Reference | Yao XQ. et al., 2004, World J Gastroenterol.?10 (9): 1262-7.,Altieri DC. 1994,?J Biol Chem.?269 (5): 3139-42.,Bouchard BA. et al., 2002,?Thromb Haemost.?86 (4): 1133-5. |
URL | https://www.targetmol.com/recombinant-protein/survivin_protein_human_recombinant |