タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03629
- 製品名称
- Syntaxin 8 Protein, Human, Recombinant (His)
- タンパク質名
- Syntaxin 8
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | CARB, syntaxin 8 |
---|---|
Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity | > 85 % as determined by SDS-PAGE |
Description | STX8, also known as syntaxin 8, directly interacts with HECTd3. STX8 forms the SNARE complex with syntaxin 7, vti1b and endobrevin. STX8 belongs to the syntaxin family. Members of this family are key molecules implicated in diverse vesicle docking and membrane fusion events. STX8 physically interacts with cystic fibrosis transmembrane conductance regulator (CFTR): recombinant syntaxin 8 binds CFTR in vitro and both proteins co-immunoprecipitate in HT29 cells. Syntaxin 8 regulates CFTR-mediated currents in chinese hamster ovary (CHO) cells stably expressing CFTR and syntaxin 8. STX8 contributes to the regulation of CFTR trafficking and chloride channel activity by the SNARE machinery. |
Reference | Zhang L. et al., 2009, Cell Mol Neurobiol. 29 (1): 115-21.,Steegmaier M. et al., 1999, J Biol Chem. 273 (51): 34171-9.,Bilan F. et al., 2004, J Cell Sci. 117 (10): 1923-35.,Thoreau V. et al., 1999, Biochem Biophys Res Commun. 257 (2): 577-83. |
URL | https://www.targetmol.com/recombinant-protein/syntaxin_8_protein_human_recombinant_his_tag_ |