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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03626
- 製品名称
- R-Spondin 1/RSPO1 Protein, Human, Recombinant
- タンパク質名
- R-Spondin 1/RSPO1
- Species
- Human
- HOST
- CHO Cells
- 20μg: -
- お問い合わせ
Overview
| Synonyms | RSPO, R-spondin 1, CRISTIN3 |
|---|---|
| Characteristics | 1. Measured by its ability to induce activation of ?catenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 10-80 ng/mL in the presence of 5 ng/mL recombinant mouse Wnt3a.<br> 2. Human intestinal cancer organoids were cultured with RSPO1, EGF, NOG. (Routinely tested).<br> 3. Human colorectum organoids were cultured with RSPO1, EGF, NOG. (Routinely tested).<br> 4. Human lung cancer organoids were cultured with FGF2, FGF4, FGF7, EGF, FGF10, NOG, RSPO1. (Routinely tested).<br> 5. Human lung organoids were cultured with FGF2, FGF4, FGF7,EGF, FGF10, NOG, RSPO1. (Routinely tested).<br> 6. Human cholangiocarcinomas organoids were cultured with FGF2, HGF, FGF7, EGF, FGF10, NOG, RSPO1. (Routinely tested).<br> 7. Human liver cancer organoids were cultured with FGF2, HGF, FGF7, EGF, FGF10, TGFB1, NOG,RSPO1. (Routinely tested).<br> 8. Human kidney cancer organoids were cultured with FGF2, FGF7, EGF, FGF10, NOG, RSPO1. (Routinely tested).<br> 9. Human kidney organoids were cultured with FGF7, EGF, FGF10,NOG, RSPO1, HGF, FGF4. (Routinely tested).<br> 10. Human gastric cancer organoids were cultured with EGF, FGF10, NOG, RSPO1. (Routinely tested).<br> 11. Human stomach organoids organoids were cultured with EGF, FGF10, NOG, RSPO1. (Routinely tested).<br> 12. Human breast cancer organoids were cultured with FGF7, RSPO1, IGF1, EGF, NRG1 Beta 1, NOG. (Routinely tested).<br> 13. Human ovarian organoids were cultured with IGF1, NRG1 Beta 1,RSPO1, EGF, NOG. (Routinely tested). |
| Endotoxin Level | < 10 EU/mg of the protein. |
| Purity | SDS-PAGE: 97.2%; SEC-HPLC: 99.2% |
| Description | R-Spondin 1/RSPO1 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q2MKA7-1. |
| Reference | Ota T, et al. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 36(1):40-5.,Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.,Kamata T, et al. (2004) R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants. Biochim Biophys Acta. 1676(1):51-62. |
| URL | https://www.targetmol.com/recombinant-protein/rspo1_protein_human_recombinant_hplc_verified |
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