IL-10 Protein, Human, Recombinant [TMPY-03547]

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Synonyms	Interleukin-10, TGIF, CSIF, IL10A, IL-10, GVHDS, interleukin 10
Characteristics	1. Immobilized human IL10 at 10 μg/mL (100 μl/well) can bind Cynomolgus IL10RA-Fc , The EC50 of Cynomolgus IL10RA-Fc is 0.24-0.56 μg/mL. 2. Measured in a cell proliferation assay using MC/9-2 mouse mast cells. The ED50 for this effect is typically 0.5-2.5 ng/mL.
Endotoxin Level	Please contact us for more information.
Purity	SDS-PAGE: 95.9%; SEC-HPLC: 91.1%
Description	IL-10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.6 kDa and the accession number is P22301.
Reference	Arimoto T, et al. (2007) Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra. Neurobiol Aging. 28(6):894-906.,Cui QQ, et al. (2011) Expression of RhoA in the lung tissue of acute lung injury rats and the influence of RhoA on the expression of IL-8 and IL-10. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 77(7): 1436-41.,HAn X, et al. (2010) Effect of cobalt protoporphyrin on hyperexpression of heme oxygenase-1 and secretion of IL-10 in rat bone marrow mesenchymal stem cells. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 18(5):1297-301.
URL	https://www.targetmol.com/recombinant-protein/il_10_protein_human_recombinant

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