IL-1R2 Protein, Human, Recombinant [TMPY-03481]

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Synonyms	IL1R2c, IL1RB, IL-1RT2, IL-1RT-2, CDw121b, IL-1R-2, CD121b, interleukin 1 receptor, type II
Characteristics	1. Measured by its binding ability in a functional ELISA. Immobilized Human IL1R2 at 2 μg/ml (100 μl/well) can bind Human IL-1 beta His , biotinylated, the EC50 of IL-1 beta His, biotinylated is 70-260 ng/mL. 2. Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500 pg/mL IL1b. The EC50 for this effect is typically 50-250 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	96.60%
Description	IL-1R2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.4 kDa and the accession number is P27930-1.
Reference	Van der Poll T, et al. (1997) Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13. J Infect Dis. 175 (1): 118-22.,Liu C, et al. (1996) Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA. J Biol Chem. 271 (34): 20965-72.,Cannon JG, et al. (1997) Interleukin-1 beta, interleukin-1 receptor antagonist, and soluble interleukin-1 receptor type II secretion in chronic fatigue syndrome. J Clin Immunol. 17 (3): 253-61.
URL	https://www.targetmol.com/recombinant-protein/il1r2_protein_human_recombinant

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