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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03274
- 製品名称
- CXCL11 Protein, Human, Recombinant
- タンパク質名
- CXCL11
- Species
- Human
- HOST
- E. coli
- 20μg: -
- お問い合わせ
Overview
| Synonyms | SCYB9B, I-TAC, chemokine (C-X-C motif) ligand 11, H174, SCYB11, IP9, b-R1, IP-9 |
|---|---|
| Characteristics | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | Please contact us for more information. |
| Purity | SDS-PAGE: > 95% |
| Description | I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family. |
| Reference | Salmaggi A,et al.(2003) Expression and modulation of IFN-gamma-inducible chemokines (IP-10, Mig, and I-TAC) in human brain endothelium and astrocytes: possible relevance for the immune invasion of the central nervous system and the pathogenesis of multiple sclerosis. J Interferon Cytokine Res. 22(6):631-40.,Rani MR,et al.(2002) Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene. J Biol Chem. 277(41): 38456-61.,Strausberg RL,et al.(2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903. |
| URL | https://www.targetmol.com/recombinant-protein/cxcl11_protein_human_recombinant |
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