IL-27 Protein, Human, Recombinant (His) [TMPY-03142]

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Synonyms	IL27p28, IL-27, IL27A, interleukin 27, p28, IL-27A, IL30
Characteristics	1. Measured by its binding ability in a functional ELISA. Immobilized human IL27-His at 10 μg/ml (100 μl/well) can bind human IL27RA-Fc , The EC50 of human IL27RA-Fc is 0.2-0.46 μg/ml. 2. Measured in antiviral assays using HepG2 cells infected with vesicular stomatitisvirus(VSV). The ED50 for this effect is typically 23-92 ng/mL.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	96.60%
Description	IL-27 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is NP_005746.2&NP_663634.2.
Reference	Hisada M, et al. (2004) Potent antitumor activity of interleukin-27. Cancer Res. 64(3): 1152-6.,Larousserie F, et al. (2005) Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus- and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. Am J Pathol. 166(4): 1217-28.,Seita J, et al. (2008) Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood. 111(4): 1903-12.
URL	https://www.targetmol.com/recombinant-protein/il_27_protein_human_recombinant_his_tag_

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