タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-03104
- 製品名称
- FGF-17 Protein, Human, Recombinant
- タンパク質名
- FGF-17
- Species
- Human
- HOST
- E. coli
- 20μg: -
- お問い合わせ
Overview
Synonyms | fibroblast growth factor 17, HH20, FGF-13, FGF-17 |
---|---|
Characteristics | Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.6-3 μg/mL. |
Endotoxin Level | Please contact us for more information. |
Purity | 99.20% |
Description | FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also required for normal brain development. |
Reference | Polnaszek N,et al.(2004) FGF17 is an autocrine prostatic epithelial growth factor and is upregulated in benign prostatic hyperplasia. Prostate. 60(1):18-24.,Xu J,et al.(2000) Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures. Development. 127(9):1833-43.,Strausberg RL,et al.(2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903. |
URL | https://www.targetmol.com/recombinant-protein/fgf17_protein_human_recombinant |