IL-17A Protein, Human, Recombinant [TMPY-02886]

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Synonyms	IL-17, interleukin 17A, CTLA8, IL17, IL-17A, CTLA-8
Characteristics	Measured by its ability to induce IL-6 secretion by NIH?3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.5-2.5 ng/mL.
Endotoxin Level	Please contact us for more information.
Purity	97.90%
Description	IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
Reference	Laan M, et al. (1999) Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol. 162(4):2347-52.,Kotake S, et al. (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest. 103(9):1345-52.,Andoh A, et al. (2002) IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. J Immunol. 169(4):1683-7.,Shin HC, et al. (1999) Regulation of IL-17, IFN-gamma and IL-10 in human CD8(+) T cells by cyclic AMP-dependent signal transduction pathway. Cytokine. 10(11):841-50.
URL	https://www.targetmol.com/recombinant-protein/il17_protein_human_recombinant

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